Auvelity is a prescription oral medication indicated for the treatment of major depressive disorder (MDD) in adults. It combines dextromethorphan, an NMDA receptor antagonist, with bupropion, a norepinephrine-dopamine reuptake inhibitor (NDRI), to offer a novel mechanism of action in managing depression.
Auvelity is not approved for use in children or for any condition other than MDD. While its components—dextromethorphan and bupropion—are found in other medications, this specific formulation is uniquely approved for depression.